EURL
European Union Reference Laboratory for
Foot-and-Mouth disease
Publications
2024
2024
Detection of foot-and-mouth disease viruses from the A/AFRICA/G-I genotype in the Sultanate of Oman
Ahmed Al-Rawahi W., Al-Riyami B., Ibrahim Elshafie E., Baqir S., Al-Ansari A., Wadsworth J., M. Hicks H., J. Knowles N., Di Nardo A., P. King D., Zientara S., Al Salloom F., Sangula A., Bernelin-Cottet C. and Bakkali-Kassimi L., Preventive Veterinary Medicine 2023
doi: 10.1016/j.prevetmed.2023.106113
Leaderless foot-and-mouth disease virus serotype O did not cause clinical disease and failed to establish a persistent infection in cattle
Litz B., Sehl-Ewert J., Breithaupt A., Landmesser A., Pfaff F., Romey A., Blaise-Boisseau S., Beer M. and Eschbaumer M., Emerging Microbes & Infections 2024
2023
2023
Host specific interplay between Foot-and-Mouth Disease Virus 3D polymerase and the type I interferon pathway
Sarry M, Caignard G, Dupré J, Zientara S, Vitour D, Bakkali-Kassimi L and Blaise-Boisseau S 2023 Viruses
Field evaluation of a safe, easy and low-cost protocol for shipment of samples from suspected cases of foot-and-mouth disease to diagnostic laboratories
Romey A, Ularamu-Hussaini G., Bulut A, Jamal-Syed M., Khan S, Ishaq M, Eschbaumer Ml, Belsham-Graham J., Bernelin-Cottet C, Relmy A, Gondard M, Benfrid S, Wungak-Yiltawe S., Hamers C, Hudelet P, Zientara S, Bakkali-Kassimi L and Blaise-Boisseau S 2023 TBED
Development of a primary cell model derived from porcine dorsal soft palate for foot-and-mouth disease virus research and diagnosis
Sarry M, Bernelin-Cottet C, Michaud C, Relmy A, Romey A, Salomez AL, Renson P, Contrant M, Berthaud M, Huet H, Jouvion G, Hägglund S, Valarcher JF, Bakkali Kassimi L, Blaise-Boisseau S. Microbiol. 2023.
doi: 10.3389/fmicb.2023.1215347
Application of the Nagoya Protocol to veterinary pathogens: concerns for the control of foot-and-mouth disease
Horsington J., Abbeloos E., Bakkali-Kassimi L., Boonsuya Seeyo K., Capozzo AV., Chepkwony E., Eblé P., Galdo-Novo S., Gizaw D., Gouverneur L., Grazioli S., Heath L., Hudelet P., Hyera JMK., Ilott M., King A., Lefebvre D., Mackay D., Metwally S., Mwiine FN., Nfon CK., Park M-K., Pituco EM., Rosso F., Simon F., Ularamu HG., Vermeij P., Vosloo W. and King DP.
doi: 10.3389/fvets.2023.1271434
2022
2022
Identification of diffusion routes of O/EA-3 topotype of foot-and-mouth disease virus in Africa and Western Asia between 1974 and 2019 - a phylogeographic analysis
Canini L, Blaise-Boisseau S, Wadsworth J, Nardo AD, Shaw A, Romey A, Relmy A, Bernelin-Cottet C, Salomez AL, Haegeman A, Ularamu H, Lefebvre D, De Clercq K, Mioulet V, Brocchi E, Pezzoni G, Nfon C, King D, Durand B, Knowles N, Kassimi LB, Benfrid S. 2022 Transbound Emerg Dis.
Characterization of the O/ME-SA/Ind-2001d foot-and-mouth disease virus epidemic recorded in the Maghreb during 2014-15
Pezzoni G, Calzolari M, Foglia EA, Bregoli A, Nardo AD, Sghaier S, Madani H, Chiapponi C, Grazioli S, Relmy A, Kassimi LB, Brocchi E. 2022 Transbound Emerg Dis.
Molecular and Serological Epidemiology of Foot-and-Mouth Disease Virus in North Region of Cameroon
Dickmu S. , Awah-Ndukum J. , Aziwo N. , Sevidzem S. , Mouliom Mouiche M. , Rueda C. , Kassimi L. , Wade A. , Garabed R. , El-Yuguda A. , Rodriguez L. and Baba S. 2022 Advances in Microbiology
Molecular Interplays with IFN Response and the Importance of the Model
Sarry, M.; Vitour, D.; Zientara, S.; Bakkali Kassimi, L.; Blaise-Boisseau, S. Viruses 2022
Le virus de la fièvre aphteuse : transmission, pathogenèse, diagnostic et surveillance
Sarry M., Romey A., Lefebvre D., Benfrid S., Dufour B., Durand B., Zanella G., De Regge N., Zientara S.; Bakkali Kassimi L. et Blaise-Boisseau S. 2022 Virologie
2021
2021
The history of foot-and-mouth disease virus serotype C: the first known extinct serotype?
Paton D J, Di Nardo A, Knowles N J, Wadsworth J, Pituco E M, Cosivi O, Rivera A M, Bakkali Kassimi L, Brocchi E, De Clercq K, Carrillo C,Maree F F, Singh R K, Vosloo W, Park M-K, Sumption K J, Ludi A B, King D P. 2021 Virus Evolution.
https://doi.org/10.1093/ve/veab009
Selection and use of reference panels: a case study highlighting current gaps in the materials available for foot and mouth disease
Ludi A B, Mioulet V, Bakkali Kassimi L, Lefebvre D J, De Clercq K, Chitsungo E, Nwankpa N, Vosloo W, Paton D J & King D P. 2021 Rev. Sci. Tech
2020
2020
The Antibody Response Induced FMDV Vaccines in Sheep Correlates with Early Transcriptomic Responses in Blood
Jouneau L, Lefebvre D J, Costa F, Romey A, Blaise-Boisseau S, Relmy A, Jaszczysyn Y, Dard-Dascot C, Dejeans S, Versillé N, Guitton E, Hudelet P, Curet M, De Clercq K, Bakkali Kassimi L, Zientara S, Klonjkowski B and Schwartz-Cornil L. 2020 NPJ Vaccines.
Model of persistent foot-and-mouth disease virus infection in multilayered cells derived from bovine dorsal soft palate
Hägglund S, Laloy E, Näslund K, Pfaff F, Eschbaumer M, Romey A, Relmy A, Rikberg A, Svensson A, Huet H, Gorna K, Zühlke D, Riedel K, Beer M, Zientara S, Bakkali Kassimi L, Blaise‐Boisseau S, J.F Valarcher. 2020 Transbound Emerg Dis.
The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood
Jouneau L, Lefebvre DJ, Costa F, Romey A, Blaise-Boisseau S, Relmy A, Jaszczyszyn Y, Dard-Dascot C, Déjean S, Versillé N, Guitton E, Hudelet P, Curet M, De Clercq K, Bakkali Kassimi L, Zientara S, Klonjkowski B, Schwartz-Cornil I. 2020 NPJ Vaccines
doi: 10.1038/s41541-019-0151-3
FMD vaccine matching: Inter laboratory study for improved understanding of r1 values
Willems T, De Vleeschauwer A, Perez-Filgueira M, Li Y, Ludi A, Lefebvre D, Wilsden G, Statham B, Haas B, Mattion N, Robiolo B, Beascoechea Perez C, Maradei E, Smitsaart E, La Torre J, De Clercq K. 2020. J Virol Methods
doi: 10.1016/j.jviromet.2019.113786
Seroprevalence and molecular characterization of foot-and-mouth disease in Chad
Abdel-Aziz AI., Romey A., Relmy A., Gorna K., Laloy E., Métras R., Munoz F., Blaise-Boisseau S., Zientara S., Lancelot R., Bakkali Kassimi L.2020. Vet Med Sci.
2019
2019
Serological and molecular epidemiology of foot-and-mouth disease viruses in agro-pastoralist livestock herds in the kachia grazing reserve, Nigeria
Ehizibolo DO, De Vleeschauwer AR, Haegeman A, Lefebvre D, Nwosuh CI, Umoh JU, Okolocha EC, Kazeem HM, Van Borm S, De Clercq K. 2019. Transbound Emerg Dis.
Proteogenomics Uncovers Critical Elements of Host Response in Bovine Soft Palate Epithelial Cells Following In Vitro Infection with Foot-And-Mouth Disease Virus
Pfaff F, Hägglund S, Zoli M, Blaise-Boisseau S, Laloy E, Koethe S, Zühlke D, Riedel K, Zientara S, Bakkali-Kassimi L, Valarcher JF, Höper D, Beer M, Eschbaumer M. 2019. Viruses 11 (1)
2018
2018
Reconstructing the Evolutionary History of Pandemic Foot-and-Mouth Disease Viruses: The Impact of Recombination within the Emerging O/ME-SA/Ind-2001 Lineage
Bachanek-Bankowska K, Di Nardo A, Wadsworth J, Mioulet V, Pezzoni G, Grazioli S, Brocchi E, Kafle SC, Hettiarachchi R, Kumarawadu PL, Eldaghayes IM, Dayhum AS, Meenowa D, Sghaier S, Madani H, Abouchoaib N, Hoang BH, Vu PP, Dukpa K, Gurung RB, Tenzin S, Wernery U, Panthumart A, Seeyo KB, Linchongsubongkoch W, Relmy A, Bakkali-Kassimi L, Scherbakov A, King DP, Knowles NJ.2018. Sci Rep 8 (1)
https://doi.org/10.1038/s41598-018-32693-8
Development and validation of a foot-and-mouth disease virus SAT serotype-specific 3ABC assay to differentiate infected from vaccinated animals
Chitray M, Grazioli S, Willems T, Tshabalala T, De Vleeschauwer A, Esterhuysen JJ, Brocchi E, De Clercq K, Maree FF. 2018. J Virol Methods
doi: 10.1016/j.jviromet.2018.02.006
A Canine Adenovirus Type 2 Vaccine Vector Confers Protection against Foot-and-Mouth Disease in Guinea Pigs
De Vleeschauwer Annebel R., Xiaocui Zhou, David J. Lefebvre, Annabelle Garnier, Fleur Watier, Charly Pignon, Sandrine A. Lacour, Stephan Zientara, Labib Bakkali-Kassimi, Kris De Clercq, Klonjkowski B. 2018. Vaccine 36 (16)
https://doi.org/10.1016/j.vaccine.2018.02.074
Complete Genome Sequences of Five Foot-and-Mouth Disease Viruses of Serotype A Isolated from Cattle in Nigeria between 2013 and 2015
Vandenbussche F, Mathijs E, Ularamu HG, Ehizibolo DO, Haegeman A, Lefebvre D, De Vleeschauwer AR, Van Borm S, De Clercq K. 2018. Genome Announc
Outbreak investigations and molecular characterization of foot-and-mouth disease viruses circulating in south-west Niger
Souley Kouato B, Elliot FM, King DP, Hyera J, Knowles NJ, Ludi AB, Mioulet V, Matlho G, De Clercq K, Thys E, Marichatou H, Issa S, Saegerman C. 2018. Transbound Emerg Dis.
Safe and Cost-Effective Protocol for Shipment of Samples from Foot-and-Mouth Disease Suspected Cases for Laboratory Diagnostic
A.Romey, A. Relmy, K. Gorna, E. Laloy, S. Zientara, S. Blaise‐Boisseau, et L. Bakkali Kassimi. 2018. Transbound Emerg Dis. 65 (1)
2017
2017
Complete Genome Sequences of Four Foot-and-Mouth Disease Viruses of Serotype South African Territories 1 (SAT 1), Topotype X, Isolated from Cattle in Nigeria in 2015
Vandenbussche F, Mathijs E, Ularamu HG, Ehizibolo DO, Haegeman A, Lefebvre D, Lazarus DD, Wungak YS, De Vleeschauwer AR, Van Borm S, De Clercq K. 2017. Genome Announc
Laboratory validation of two real-time RT-PCR methods with 5'-tailed primers for an enhanced detection of foot-and-mouth disease virus
Vandenbussche F, Lefebvre DJ, De Leeuw I, Van Borm S, De Clercq K. 2017. J Virol Methods
doi: 10.1016/j.jviromet.2017.04.014
Foot-and-mouth disease virus serotype SAT1 in cattle, Nigeria
Ehizibolo DO, Haegeman A, De Vleeschauwer AR, Umoh JU, Kazeem HM, Okolocha EC, Van Borm S, De Clercq K. 2017 Transbound Emerg Dis.
Detection and Molecular Characterization of Foot and Mouth Disease Viruses from Outbreaks in Some States of Northern Nigeria 2013-2015
Ehizibolo DO, Haegeman A, De Vleeschauwer AR, Umoh JU, Kazeem HM, Okolocha EC, Van Borm S, De Clercq K. 2017. Transbound Emerg Dis.
Genetic Characterization of Serotypes A and Asia-1 Foot-and-Mouth Disease Viruses in Balochistan, Pakistan, in 2011
A.Ullah, S. M. Jamal, A. Romey, K. Gorna, M. A. Kakar, F. Abbas, J. Ahmad, S. Zientara, et L. Bakkali Kassimi. 2017. Transbound Emerg Dis.64 (5)
2016
2016
A Tale of Tails: Dissecting the Enhancing Effect of Tailed Primers in Real-Time PCR
Vandenbussche F, Mathijs E, Lefebvre D, De Clercq K, Van Borm S. 2016. PLoS One
doi: 10.1371/journal.pone.0164463
Establishment and Validation of Two Duplex One-Step Real-Time RT-PCR Assays for Diagnosis of Foot-and-Mouth Disease
K.Gorna, A. Relmy, A. Romey, S. Zientara, S. Blaise-Boisseau, et L. Bakkali-Kassimi. 2016.J Virol Methods 235
https://doi.org/10.1016/j.jviromet.2016.03.020
A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds
De Vleeschauwer AR, Lefebvre DJ, Willems T, Paul G, Billiet A, Murao LE, Neyts J, Goris N, De Clercq K. 2014. Transbound Emerg Dis.
2015
2015
Establishment of Persistent Foot-and-Mouth Disease Virus (FMDV) Infection in MDBK Cells
Kopliku Lela, Anthony Relmy, Aurore Romey, Kamila Gorna, Stephan Zientara, Labib Bakkali-Kassimi, et Sandra Blaise-Boisseau. 2015. Arch Virol 160 (10)
https://doi.org/10.1007/s00705-015-2526-8
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family
van der Linden L, Vives-Adrián L, Selisko B, Ferrer-Orta C, Liu X, Lanke K, Ulferts R, De Palma AM, Tanchis F, Goris N, Lefebvre D, De Clercq K, Leyssen P, Lacroix C, Pürstinger G, Coutard B, Canard B, Boehr DD, Arnold JJ, Cameron CE, Verdaguer N, Neyts J, van Kuppeveld FJ. 2015. PLoS Pathog
2014
2014
A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus
Lefebvre DJ, De Vleeschauwer AR, Goris N, Van Borm S, Chimirri A, Monforte AM, Valdazo-Gonzalez B, King DP, Neyts J, De Clercq K. 2014. Biochem Biophys Res Commun.
doi: 10.1016/j.bbrc.2014.11.023
In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks
Osiceanu AM, Murao LE, Kollanur D, Swinnen J, De Vleeschauwer AR, Lefebvre DJ, De Clercq K, Neyts J, Goris N. 2014. Antiviral Res.
doi: 10.1016/j.antiviral.2014.02.009
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases
van der Linden L, Ulferts R, Nabuurs SB, Kusov Y, Liu H, George S, Lacroix C, Goris N, Lefebvre D, Lanke KH, De Clercq K, Hilgenfeld R, Neyts J, van Kuppeveld FJ. 2014. Antiviral Res.
doi: 10.1016/j.antiviral.2013.12.012
Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice
Lefebvre DJ, De Vleeschauwer AR, Goris N, Kollanur D, Billiet A, Murao L, Neyts J, De Clercq K. 2014. Transbound Emerg Dis.
The use of serosurveys following emergency vaccination, to recover the status of "foot-and-mouth disease free where vaccination is not practised"
Paton DJ, Füssel AE, Vosloo W, Dekker A, De Clercq K. 2014. Vaccine
doi: 10.1016/j.vaccine.2014.10.064
First Isolation and Molecular Characterization of Foot-and-Mouth Disease Virus in Benin
K.Gorna, E. Houndjè, A. Romey, A. Relmy, S. Blaise-Boisseau, M. Kpodékon, C. Saegerman, F. Moutou, S. Zientara, et L. Bakkali Kassimi. 2014. Vet Microbiol 171 (1)