EURL rabies
Collection of samples, techniques, validation and interpretation of the diagnostic methods for the purposes of rabies surveillance are presented here.
Diagnostic methods considered compliant are presented in the WOAH rabies manual. A list of procedures inspired by the WOAH official methods is also proposed.
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European Union Reference Laboratoryteam presentation About the laboratory
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The EURL team, under the direction of Dr. Florence Cliquet, has a full time staff of 3 for the Lyssavirus Unit. Director of the EURL for rabies Dr. Florence Cliquet: Senior Scientist; PhD in Immunology; 21 years of experience in rabies; Head of the Lyssavirus unit; Head of the rabies serology EURL and the rabies EURL; Head of the WHO Collaborating Centre; OIE rabies expert Head of rabies E-RL project Dr. Emmanuelle Robardet: Scientist; PhD in Epidemiology; Head of the Rabies EURL Rabies EURL technical scientist Sabrina Andrieu Rabies EURL administrative officer Sylvie Tourdiat The Lyssavirus Unit represented by 15 agents is headed by Dr Florence Cliquet. Each scientist of the Lyssavirus Unit can provide expertise, scientific and technical support under the rabies EURL mandate in accordance with their specialty (diagnosis, molecular biology, bait titration, virology, etc.). Dr. Evelyne Picard-Meyer: Scientist; PhD in molecular biology; 12 years of experience in rabies diagnosis and molecular epidemiology; Deputy Head of the Lyssavirus Unit. Dr. Jacques Barrat: Doctor of Veterinary Medecine; 30 years of experience in rabies; OIE rabies expert; Head of animal experimentation. Marine Wasniewski: Scientific engineer; Head of the Rabies serology EURL; Head of virology section; responsible for immunology work in seroneutralisation tests. Alexandre Servat: Scientific engineer; Head of vaccinology section and diagnosis. Jean-Michel Demerson: Head technician; 25 years of experience in fox ecology and in field rabies oral vaccination programmes using aerial and manual methods.
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Group picture of the Lyssavirus Unit
Contact us For any enquiry, please contact us by email specifying: - “rabies” in the object - your name, laboratory and function in the message The messages without “rabies” in the object will be destroyed without being read.
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last update: May 2013
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Home Rabies disease The lab Duties of the EURL EURL Team presentation Training and development Work on rabies by Nancy laboratory Other international activities NRLs The network National Reference Laboratories presentation EC rules Useful information Links Map and directions Contact us
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News, calendar Documentation Periodical publications Work programmes Technical reports Workshops Proficiency tests Protocols Other documentation Strain database Presentation All data Advanced search in database Submit data Reagents
Rabies disease
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Home Rabies disease The lab Duties of the EURL EURL Team presentation Training and development Work on rabies by Nancy laboratory Other international activities NRLs The network National Reference Laboratories presentation EC rules Useful information Links Map and directions Contact us
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News, calendar Documentation Periodical publications Work programmes Technical reports Workshops Proficiency tests Protocols Other documentation Strain database Presentation All data Advanced search in database Submit data Reagents
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Rabies is a zoonosis (animal disease that can be transmitted to humans) caused by a virus of the genus Lyssavirus. Found in the saliva of infected animals in the final phases of the disease, the virus is generally transmitted to another animal or to humans through biting. Contamination may also occur if the saliva of an infected animal comes into contact with a wound or a mucous membrane. There are 11 different genotypes of rabies virus, seven of which transmission to human has already been notified. Genotypes are mainly differentiated according to the animal host species. Rabies in carnivores is usually caused by the genotype 1 virus, which is the most commonly identified in human rabies cases. Without treatment prior to the onset of clinical signs, the disease is always fatal. Rabies, which causes over 55,000 deaths a year worldwide, is found all over the world, except in certain areas such as Australia and the British Isles due to their geographical particularities. Several European countries have become rabies-free thanks to oral vaccination programmes. In industrialised countries, rabies persists mainly in wild animals whereas it remains an endemic disease in many developing countries, with the domestic dog as the principal reservoir and main source of human contamination. In Western European Countries, rabies in dogs was eliminated several decades ago, but it continues to persist in fox populations. Thanks to oral vaccination campaigns conducted in foxes, vulpine rabies (i.e. rabies affecting foxes) has been eliminated in France. The last case was reported in 1998. France therefore now fulfils the OIE conditions enabling it to be declared a rabies-free country. To avoid any risk of reintroduction, the rabies situation in France is monitored on an ongoing basis. The illegal importation of infected animals from Africa remains a concern, and justifiably so since seven cases have been detected in France since 2001. Certain types of rabies, however, can affect bats (chiroptera). In Europe, bat rabies viruses belong to genotypes 5 and 6. While these can infect humans, the risk of virus transmission from bats to humans is considered negligible in the general population considering the low probability of human exposure to bats. Since 1970, 20 human cases of rabies have occurred in France; all of them were the result of contamination occurring outside of France.
More documentation
> " Rabies card " (pdf, in french) > More animal disease cards
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www.anses.fr | Copyright | Portal Anses websites
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last update: May 2013